Role of Enzymes in Piglets

The purpose of this research is to determine the impact of whey on transaminases, which are indicators of liver disease. For this purpose, two groups of piglets were fed with different amounts of whey (ad libidum and controlled quantity) in the period of 45 days. Every 15 days values were tested for ALT, AST and ɣ -GT serum of piglets, and these parameters were examined in vitro with pathological and normal control serum. From several samples of whey investigated total protein and albumen, as minerals Fe, K, Ca and P, using a spectrophotometric method. In piglets fed by whey, a significant reduction is obtained in the level of transaminases (p <0.05) the lowest values and the smallest deviation values were obtained in the group of piglets which were fed ad libidum. The results in vitro show that whey performed inhibition on the activity of these enzymes ALT 10,71%, AST 8,51% and ɣ -GT from 18.16% in pathological serum, in serum with normal values, whey performed inhibition on ALT for 39.33%, AST for 29.08% and ɣ -GT for 39.59%. Whey impacts on the reduction of transaminases and performs inhibition of enzyme activity in the in vitro test.

Keywords: ALT, AST, ɣ -GT, piglets, whey, enzymes in vivo, enzymes in vitro.